Study of promising Alzheimer’s marker in blood prompts warning about brain-boosting supplements

Journal Reference: Xu Chen, Riccardo Calandrelli, John Girardini, Zhangming Yan, Zhiqun Tan, Xiangmin Xu, Annie Hiniker, Sheng Zhong. PHGDH expression increases with progression of Alzheimer’s disease pathology and symptoms. Cell Metabolism, 2022; 34 (5): 651 DOI: 10.1016/j.cmet.2022.02.008 The findings also prompt caution against the use of dietary supplements that contain the amino acid serine as … Read more

Dementia: Combination of ’emotions’ and measurements suggest Alzheimer’s in the early stage

Journal Reference: Frank Jessen, Steffen Wolfsgruber, Luca Kleineindam, Annika Spottke, Slawek Altenstein, Claudia Bartels, Moritz Berger, Frederic Brosseron, Marcel Daamen, Martin Dichgans, Laura Dobisch, Michael Ewers, Friederike Fenski, Klaus Fliessbach, Silka D. Freiesleben, Wenzel Glanz, Doreen Görß, Selim Gürsel, Daniel Janowitz, Ingo Kilimann, Xenia Kobeleva, Andrea Lohse, Franziska Maier, Coraline Metzger, Matthias Munk, Lukas Preis, … Read more

Quantifying cognitive decline in dogs could help humans with Alzheimer’s disease

Journal Reference: Gilad Fefer, Wojciech K. Panek, Michael Z. Khan, Matthew Singer, Hans Westermeyer, Freya M. Mowat, David M. Murdoch, Beth Case, Natasha J. Olby, Margaret E. Gruen. Use of Cognitive Testing, Questionnaires, and Plasma Biomarkers to Quantify Cognitive Impairment in an Aging Pet Dog Population. Journal of Alzheimer’s Disease, 2022; 1 DOI: 10.3233/JAD-215562 Canine … Read more

Study preserves memory in mice, offering promising new basis for active immunization against Alzheimer’s disease

Study preserves memory in mice, offering promising new basis for active immunization against Alzheimer’s disease – NovLink Home Mash I Study preserves memory in mice, offering promising new basis for active immunization against Alzheimer’s disease We would like to give thanks to the author of this article for this remarkable content Study preserves memory in … Read more

Study identifies therapeutic target for Alzheimer’s disease, revealing strategy for preventing or slowing disease progression

Study identifies therapeutic target for Alzheimer’s disease, revealing strategy for preventing or slowing disease progression – NovLink Home Mash I Study identifies therapeutic target for Alzheimer’s disease, revealing strategy for preventing or slowing disease progression We would love to thank the author of this write-up for this remarkable material Study identifies therapeutic target for Alzheimer’s … Read more

Study reports potential target and compounds to slow the development of Alzheimer’s disease

Journal Reference: Khanh V. Do, Erik Hjorth, Ying Wang, Bokkyoo Jun, Marie-Audrey I. Kautzmann, Makiko Ohshima, Maria Eriksdotter, Marianne Schultzberg, Nicolas G. Bazan. Cerebrospinal Fluid Profile of Lipid Mediators in Alzheimer’s Disease. Cellular and Molecular Neurobiology, 2022; DOI: 10.1007/s10571-022-01216-5 Specialized lipid mediators are bioactive compounds composed of polyunsaturated fatty acids like DHA and EPA. They … Read more

Loss of neurons, not lack of sleep, makes Alzheimer’s patients drowsy

Journal Reference: Jun Y. Oh, Christine M. Walsh, Kamalini Ranasinghe, Mihovil Mladinov, Felipe L. Pereira, Cathrine Petersen, Neus Falgàs, Leslie Yack, Tia Lamore, Rakin Nasar, Caroline Lew, Song Li, Thomas Metzler, Quentin Coppola, Natalie Pandher, Michael Le, Hilary W. Heuer, Helmut Heinsen, Salvatore Spina, William W. Seeley, Joel Kramer, Gil D. Rabinovici, Adam L. Boxer, … Read more

Alzheimer‘s: Amyloid and tau are a perilous couple

Journal Reference: Emrah Düzel, Gabriel Ziegler, David Berron, Anne Maass, Hartmut Schütze, Arturo Cardenas-Blanco, Wenzel Glanz, Coraline Metzger, Laura Dobisch, Martin Reuter, Annika Spottke, Frederic Brosseron, Klaus Fliessbach, Michael T Heneka, Christoph Laske, Oliver Peters, Josef Priller, Eike Jakob Spruth, Alfredo Ramirez, Oliver Speck, Anja Schneider, Stefan Teipel, Ingo Kilimann, Wiltfang Jens, Björn-Hendrik Schott, Lukas … Read more

Promising Alzheimer’s drug may also improve memory in Down syndrome and normal aging

Journal Reference: Md. Mahiuddin Ahmed, Athena Ching-Jung Wang, Mihret Elos, Heidi J. Chial, Stefan Sillau, D. Adriana Solano, Christina Coughlan, Leila Aghili, Paige Anton, Neil Markham, Vanesa Adame, Katheleen J. Gardiner, Timothy D. Boyd, Huntington Potter. The innate immune system stimulating cytokine GM-CSF improves learning/memory and interneuron and astrocyte brain pathology in Dp16 Down syndrome … Read more

Lipid and glucose levels at age 35 associated with Alzheimer’s disease

Journal Reference: Xiaoling Zhang, Tong Tong, Andrew Chang, Ting Fang Alvin Ang, Qiushan Tao, Sanford Auerbach, Sherral Devine, Wei Qiao Qiu, Jesse Mez, Joseph Massaro, Kathryn L. Lunetta, Rhoda Au, Lindsay A. Farrer. Midlife lipid and glucose levels are associated with Alzheimer’s disease. Alzheimer’s & Dementia, 2022; DOI: 10.1002/alz.12641 “While our findings confirm other studies … Read more

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