Heavy metal pollution can increase antibiotic resistance in rivers

Journal Reference: Sonia Gupta, David W. Graham, T.R. Sreekrishnan, Shaikh Ziauddin Ahammad. Effects of heavy metals pollution on the co-selection of metal and antibiotic resistance in urban rivers in UK and India. Environmental Pollution, 2022; 306: 119326 DOI: 10.1016/j.envpol.2022.119326 Research by Newcastle University and the Indian Institute of Technology, Delhi quantified antibiotic and metal resistance … Read more

Antibiotic and antiretroviral drug effects on breast milk are explored for mothers living with HIV

Journal Reference: Rabia Maqsood, Peter T. Skidmore, LaRinda A. Holland, Joshua L. Au, Adam K. Khan, Lily I. Wu, Ningxin Ma, Emily R. Begnel, Bhavna H. Chohan, Judith Adhiambo, Grace John-Stewart, James Kiarie, John Kinuthia, Michael H. Chung, Barbra A. Richardson, Jennifer Slyker, Dara A. Lehman, Efrem S. Lim. Dynamic Changes in Breast Milk Microbiome … Read more

How a narrow-spectrum antibiotic takes aim at C. Diff

Journal Reference: Xinyun Cao, Hande Boyaci, James Chen, Yu Bao, Robert Landick, Elizabeth A. Campbell. Basis of narrow-spectrum activity of fidaxomicin on Clostridioides difficile. Nature, 2022; DOI: 10.1038/s41586-022-04545-z The answer to this problem might be narrow-spectrum antibiotics that kill only one or a few species of bacteria, minimizing the risk of collateral damage. In a … Read more

Study connects shorter course of antibiotics to fewer antibiotic resistance genes

Journal Reference: M. M. Pettigrew, J. Kwon, J. F. Gent, Y. Kong, M. Wade, D. J. Williams, C. B. Creech, S. Evans, Q. Pan, E. B. Walter, J. M. Martin, J. S. Gerber, J. G. Newland, M. E. Hofto, M. A. Staat, V. G. Fowler, H. F. Chambers, W. C. Huskins. Comparison of the Respiratory … Read more

Higher dose antibiotic shown safe in TB patients likely more effective in treating deadliest form of TB

Journal Reference: Camilo A. Ruiz-Bedoya, Filipa Mota, Elizabeth W. Tucker, Farina J. Mahmud, Maria I. Reyes-Mantilla, Clara Erice, Melissa Bahr, Kelly Flavahan, Patricia de Jesus, John Kim, Catherine A. Foss, Charles A. Peloquin, Dima A. Hammoud, Alvaro A. Ordonez, Carlos A. Pardo, Sanjay K. Jain. High-dose rifampin improves bactericidal activity without increased intracerebral inflammation in … Read more

Machine learning antibiotic prescriptions can help minimize resistance spread

Journal Reference: Mathew Stracy, Olga Snitser, Idan Yelin, Yara Amer, Miriam Parizade, Rachel Katz, Galit Rimler, Tamar Wolf, Esma Herzel, Gideon Koren, Jacob Kuint, Betsy Foxman, Gabriel Chodick, Varda Shalev, Roy Kishony. Minimizing treatment-induced emergence of antibiotic resistance in bacterial infections. Science, 2022; 375 (6583): 889 DOI: 10.1126/science.abg9868 The paper, published today in Science, is … Read more

Chemical synthesis yields potential antibiotic

Journal Reference: Kyan A. D’Angelo, Carly K. Schissel, Bradley L. Pentelute, Mohammad Movassaghi. Total synthesis of himastatin. Science, 2022; 375 (6583): 894 DOI: 10.1126/science.abm6509 Using their new synthesis, the researchers were able not only to produce himastatin but also to generate variants of the molecule, some of which also showed antimicrobial activity. They also discovered … Read more

A new way to disarm antibiotic resistance in deadly bacteria

Journal Reference: Nikol Kaderabkova, R Christopher D Furniss, Declan Barker, Patricia Bernal, Evgenia Maslova, Amanda AA Antwi, Helen E McNeil, Hannah L Pugh, Laurent Dortet, Jessica MA Blair, Gerald Larrouy-Maumus, Ronan R McCarthy, Diego Gonzalez, Despoina AI Mavridou. Breaking antimicrobial resistance by disrupting extracytoplasmic protein folding. eLife, 2022; 11 DOI: 10.7554/eLife.57974 A team of researchers … Read more

Lower antibiotic resistance in intestinal bacteria with forgotten antibiotic

Journal Reference: Charlotta Edlund, Anders Ternhag, Gunilla Skoog Ståhlgren, Petra Edquist, Åse Östholm Balkhed, Simon Athlin, Emeli Månsson, Maria Tempé, Jakob Bergström, Christian G Giske, Håkan Hanberger, Charlotta Edlund, Anders Ternhag, Gunilla Skoog Ståhlgren, Petra Edquist, Åse Östholm Balkhed, Simon Athlin, Emeli Månsson, Maria Tempé, Jakob Bergström, Christian G Giske, Daniel Holmström, Anna-Karin Lindgren, Gisela … Read more

New research moves closer to harnessing viruses to fight bacteria and reduce antibiotic use

New research moves closer to harnessing viruses to fight bacteria and reduce antibiotic use – NovLink Home Mash C New research moves closer to harnessing viruses to fight bacteria and reduce antibiotic use We would like to say thanks to the writer of this short article for this awesome material New research moves closer to … Read more

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