Make no bones about it: How our bodies shift between making bones and breaking them down

Journal Reference: Maki Uenaka, Erika Yamashita, Junichi Kikuta, Akito Morimoto, Tomoka Ao, Hiroki Mizuno, Masayuki Furuya, Tetsuo Hasegawa, Hiroyuki Tsukazaki, Takao Sudo, Keizo Nishikawa, Daisuke Okuzaki, Daisuke Motooka, Nobuyoshi Kosaka, Fuminori Sugihara, Thomas Boettger, Thomas Braun, Takahiro Ochiya, Masaru Ishii. Osteoblast-derived vesicles induce a switch from bone-formation to bone-resorption in vivo. Nature Communications, 2022; 13 … Read more

Sonic advance: How sound waves could help regrow bones

Journal Reference: Lizebona August Ambattu, Amy Gelmi, Leslie Y. Yeo. Short‐Duration High Frequency MegaHertz‐Order Nanomechanostimulation Drives Early and Persistent Osteogenic Differentiation in Mesenchymal Stem Cells. Small, 2022; 2106823 DOI: 10.1002/smll.202106823 The innovative stem cell treatment from researchers at RMIT University in Melbourne, Australia, offers a smart way forward for overcoming some of the field’s biggest … Read more

On the “Road of Bones”, paved with the bodies of Gulag prisoners

By Isabelle Mandraud Posted today at 05:43, updated at 09:32 Reserved for our subscribers In images, in picturesKolyma, an icy desert in northeastern Russia, is synonymous with the worst hours in Soviet history. The path that leads there was built from 1932 to 1953 by prisoners who perished there. An abandoned region, where the remnants … Read more

New target may help protect bones as we age

Journal Reference: Jessica L Pierce, Anuj K Sharma, Rachel L Roberts, Kanglun Yu, Debra L Irsik, Vivek Choudhary, Jennifer S Dorn, Husam Bensreti, Reginald D Benson, Helen Kaiser, Andrew Khayrullin, Colleen Davis, Chase J Wehrle, Maribeth H Johnson, Wendy B Bollag, Mark W Hamrick, Xingming Shi, Carlos M Isales, Meghan E McGee‐Lawrence. The Glucocorticoid Receptor … Read more

Thin and brittle bones strongly linked to women’s heart disease risk

Journal Reference: Jiesuck Park, Yeonyee Elizabeth Yoon, Kyoung Min Kim, In-Chang Hwang, Wonjae Lee, Goo-Yeong Cho. Prognostic value of lower bone mineral density in predicting adverse cardiovascular disease in Asian women. Heart, 2021; heartjnl-2020-318764 DOI: 10.1136/heartjnl-2020-318764 Osteoporosis, often dubbed brittle bone disease, is common, particularly among women after the menopause. It is characterised by thinning … Read more