Researchers develop new antibody test to diagnose MS

Journal Reference: Ruba S. Saadeh, Sandra C. Bryant, Andrew McKeon, Brian Weinshenker, David L. Murray, Sean J. Pittock, Maria Alice V. Willrich. CSF Kappa Free Light Chains: Cutoff Validation for Diagnosing Multiple Sclerosis. Mayo Clinic Proceedings, 2021; DOI: 10.1016/j.mayocp.2021.09.014 An antibody typically consists of two immunoglobulin heavy chains and two light chains. There are two … Read more

Digital toolbox may help diagnose dementia earlier

Journal Reference: Mengtian Du, Stacy L. Andersen, Stephanie Cosentino, Robert M. Boudreau, Thomas T. Perls, Paola Sebastiani. Digitally generated Trail Making Test data: Analysis using hidden Markov modeling. Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2022; 14 (1) DOI: 10.1002/dad2.12292 While cognitive function is often measured using paper and pencil tests with scores calculated … Read more

Immuno-CRISPR assay could help diagnose kidney transplant rejection early on

Journal Reference: Inseon Lee, Seok-Joon Kwon, Mirco Sorci, Peter S. Heeger, Jonathan S. Dordick. Highly Sensitive Immuno-CRISPR Assay for CXCL9 Detection. Analytical Chemistry, 2021; 93 (49): 16528 DOI: 10.1021/acs.analchem.1c03705 Kidney transplant recipients must take immunosuppressant drugs for the rest of their lives to help keep their immune systems from attacking the foreign organ. However, kidney … Read more