Discovery of cell protein that keeps Kaposi’s sarcoma herpesvirus dormant

Journal Reference: Ashish Kumar, Yuanzhi Lyu, Yuichi Yanagihashi, Chanikarn Chantarasrivong, Vladimir Majerciak, Michelle Salemi, Kang-Hsin Wang, Tomoki Inagaki, Frank Chuang, Ryan R. Davis, Clifford G. Tepper, Kazushi Nakano, Chie Izumiya, Michiko Shimoda, Ken-ichi Nakajima, Alexander Merleev, Zhi-Ming Zheng, Mel Campbell, Yoshihiro Izumiya. KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by … Read more

New discovery in animal exoskeletons leads to advances in designing construction materials

Journal Reference: Wei Wang, Shu Jian Chen, Weiqiang Chen, Wenhui Duan, Jia Zie Lai, Kwesi Sagoe-Crentsil. Damage-tolerant material design motif derived from asymmetrical rotation. Nature Communications, 2022; 13 (1) DOI: 10.1038/s41467-022-28991-5 In a paper published in Nature Communications, Professor Wenhui Duan from the Department of Civil Engineering at Monash University says the new pattern, adding … Read more

Abundant ‘secret doors’ on human proteins could reshape drug discovery

Journal Reference: Andre J. Faure, Júlia Domingo, Jörn M. Schmiedel, Cristina Hidalgo-Carcedo, Guillaume Diss, Ben Lehner. Mapping the energetic and allosteric landscapes of protein binding domains. Nature, 2022; 604 (7904): 175 DOI: 10.1038/s41586-022-04586-4 A ground-breaking new technique developed by researchers at the Centre for Genomic Regulation (CRG) in Barcelona has revealed the existence of a … Read more

DNA discovery reveals a critical ‘accordion impact’ for switching off genes

Journal Reference: Andrew Keniry, Natasha Jansz, Linden J. Gearing, Iromi Wanigasuriya, Joseph Chen, Christian M. Nefzger, Peter F. Hickey, Quentin Gouil, Joy Liu, Kelsey A. Breslin, Megan Iminitoff, Tamara Beck, Andres Tapia del Fierro, Lachlan Whitehead, Andrew Jarratt, Sarah A. Kinkel, Phillippa C. Taberlay, Tracy Willson, Miha Pakusch, Matthew E. Ritchie, Douglas J. Hilton, Jose … Read more

Pivotal battery discovery could impact transportation and the grid

Journal Reference: Gui-Liang Xu, Xiang Liu, Xinwei Zhou, Chen Zhao, Inhui Hwang, Amine Daali, Zhenzhen Yang, Yang Ren, Cheng-Jun Sun, Zonghai Chen, Yuzi Liu, Khalil Amine. Native lattice strain induced structural earthquake in sodium layered oxide cathodes. Nature Communications, 2022; 13 (1) DOI: 10.1038/s41467-022-28052-x Battery-powered vehicles have made a significant dent in the transportation market. … Read more

New tool to accelerate drug discovery

Journal Reference: Arfaxad Reyes-Alcaraz, Emilio Y. Lucero Garcia-Rojas, Elizabeth A. Merlinsky, Jae Young Seong, Richard A. Bond, Bradley K. McConnell. A NanoBiT assay to monitor membrane proteins trafficking for drug discovery and drug development. Communications Biology, 2022; 5 (1) DOI: 10.1038/s42003-022-03163-9 Now, for the first time, new technology developed at the University of Houston College … Read more

New enzyme discovery is another leap towards beating plastic waste

Journal Reference: William M. Kincannon, Michael Zahn, Rita Clare, Jessica Lusty Beech, Ari Romberg, James Larson, Brian Bothner, Gregg T. Beckham, John E. McGeehan, Jennifer L. DuBois. Biochemical and structural characterization of an aromatic ring–hydroxylating dioxygenase for terephthalic acid catabolism. Proceedings of the National Academy of Sciences, 2022; 119 (13) DOI: 10.1073/pnas.2121426119 They have characterised … Read more

Discovery of novel brain fear mechanisms offers target for anxiety-reducing drugs

Journal Reference: Elena Paci, Charlotte Lawrenson, Jasmine Pickford, Robert AR Drake, Bridget M Lumb, Richard Apps. Cerebellar modulation of memory encoding in the periaqueductal grey and fear behaviour. eLife, 2022; 11 DOI: 10.7554/eLife.76278 Existing anxiety-reducing drugs are not always effective for all patients and often have unwanted side effects. Understanding the brain networks and mechanisms … Read more

New toolkit aids discovery of mineral deposits crucial to ‘inexperienced economic system’ transition

Journal Reference: Lawrence C. Carter, Ben J. Williamson. Textural indicators of mineralisation potential in porphyry magmatic systems – A framework from the archetypal Yerington district, Nevada. Ore Geology Reviews, 2022; 143: 104783 DOI: 10.1016/j.oregeorev.2022.104783 A study led by Lawrence Carter from the University of Exeter’s Camborne School of Mines, has given fascinating new insights into … Read more

Scientists announce discovery of supermassive binary black holes

Journal Reference: S. O’Neill, S. Kiehlmann, A. C. S. Readhead, M. F. Aller, R. D. Blandford, I. Liodakis, M. L. Lister, P. Mróz, C. P. O’Dea, T. J. Pearson, V. Ravi, M. Vallisneri, K. A. Cleary, M. J. Graham, K. J. B. Grainge, M. W. Hodges, T. Hovatta, A. Lähteenmäki, J. W. Lamb, T. J. … Read more