Designer neurons offer new hope for treatment of Parkinson’s disease

Journal Reference: Benjamin M. Hiller, David J. Marmion, Cayla A. Thompson, Nathaniel A. Elliott, Howard Federoff, Patrik Brundin, Virginia B. Mattis, Christopher W. McMahon, Jeffrey H. Kordower. Optimizing maturity and dose of iPSC-derived dopamine progenitor cell therapy for Parkinson’s disease. npj Regenerative Medicine, 2022; 7 (1) DOI: 10.1038/s41536-022-00221-y In new research, Jeffrey Kordower and his … Read more

Hot Cannes Package: Woody Harrelson, Simu Liu, Djimon Hounsou In ‘Last Breath,’ Alex Parkinson’s Narrative Remake Of His Harrowing Docu

Hot Cannes Package Woody Harrelson Simu Liu Djimon Hounsou In

EXCLUSIVE: In what is sure to be one of the hot packages of the upcoming Cannes Market, Woody Harrelson, Shang-Chi’s Simu Liu and Djimon Hounsou are set to star in Last Breath, a fact-based narrative thriller that will be directed by Alex Parkinson. He co-directed with Richard da Costa the 2019 documentary of the same … Read more

Plant product shows promise in mouse model of Parkinson’s Disease

Journal Reference: Cheng-Peng Sun, Jun-Jun Zhou, Zhen-Long Yu, Xiao-Kui Huo, Juan Zhang, Christophe Morisseau, Bruce D. Hammock, Xiao-Chi Ma. Kurarinone alleviated Parkinson’s disease via stabilization of epoxyeicosatrienoic acids in animal model. Proceedings of the National Academy of Sciences, 2022; 119 (9): e2118818119 DOI: 10.1073/pnas.2118818119 The team found that a soluble epoxide hydrolase (sEH) inhibitor combined … Read more

Treatment for Parkinson’s could now get even better

Journal Reference: Débora Masini, Ole Kiehn. Targeted activation of midbrain neurons restores locomotor function in mouse models of parkinsonism. Nature Communications, 2022; 13 (1) DOI: 10.1038/s41467-022-28075-4 Parkinson’s is a neurodegenerative disease where dopaminergic neurons progressively die in the brainstem. Tremor and difficulties to walk are recognizable movement symptoms for many people suffering from Parkinson’s. Over … Read more

Parkinson’s protein blueprint could help fast-track new treatments

Journal Reference: Zhong Yan Gan, Sylvie Callegari, Simon A. Cobbold, Thomas R. Cotton, Michael J. Mlodzianoski, Alexander F. Schubert, Niall D. Geoghegan, Kelly L. Rogers, Andrew Leis, Grant Dewson, Alisa Glukhova, David Komander. Activation mechanism of PINK1. Nature, 2021; DOI: 10.1038/s41586-021-04340-2 The research, published in Nature, has for the first time produced a ‘live action’ … Read more

SARS-CoV-2 protein interacts with Parkinson’s protein, promotes amyloid formation, study finds

SARS-CoV-2 protein interacts with Parkinson’s protein, promotes amyloid formation, study finds – NovLink Home Mash I SARS-CoV-2 protein interacts with Parkinson’s protein, promotes amyloid formation, study finds We wish to give thanks to the writer of this short article for this remarkable material SARS-CoV-2 protein interacts with Parkinson’s protein, promotes amyloid formation, study finds

Are scientists homing in on a cure for Parkinson’s illness?

Journal Reference: Richard M. Meade, Kathryn J.C. Watt, Robert J. Williams, Jody M. Mason. A Downsized and Optimised Intracellular Library-Derived Peptide Prevents Alpha-Synuclein Primary Nucleation and Toxicity Without Impacting Upon Lipid Binding. Journal of Molecular Biology, 2021; 433 (24): 167323 DOI: 10.1016/j.jmb.2021.167323 Professor Jody Mason, who led the research from the Department of Biology and … Read more

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