Six lithium dose predictors for patients with bipolar disorder

Journal Reference: Vincent Millischer, Granville J Matheson, Sarah E Bergen, Brandon J Coombes, Katja Ponzer, Fredrik Wikström, Karolina Jagiello, Martin Lundberg, Peter Stenvinkel, Joanna M Biernacka, Olof Breuer, Lina Martinsson, Mikael Landén, Lena Backlund, Catharina Lavebratt, Martin Schalling, ,. Improving lithium dose prediction using population pharmacokinetics and pharmacogenomics: a cohort genome-wide association study in Sweden. … Read more

‘Digital twins,’ an aid to give individual patients the right treatment at the right time

Journal Reference: Xinxiu Li, Eun Jung Lee, Sandra Lilja, Joseph Loscalzo, Samuel Schäfer, Martin Smelik, Maria Regina Strobl, Oleg Sysoev, Hui Wang, Huan Zhang, Yelin Zhao, Danuta R. Gawel, Barbara Bohle, Mikael Benson. A dynamic single cell-based framework for digital twins to prioritize disease genes and drug targets. Genome Medicine, 2022; 14 (1) DOI: 10.1186/s13073-022-01048-4 … Read more

Patients with past cancer history not associated with higher risk of COVID-19-related death or hospitalization

Patients with past cancer history not associated with higher risk of COVID-19-related death or hospitalization – NovLink Home Mash T Patients with past cancer history not associated with higher risk of COVID-19-related death or hospitalization We want to thank the author of this post for this awesome content Patients with past cancer history not associated … Read more

Primary care medical home found to be more effective than usual care in treating patients with serious mental illness

Primary care medical home found to be more effective than usual care in treating patients with serious mental illness – NovLink Home Mash H Primary care medical home found to be more effective than usual care in treating patients with serious mental illness We would like to thank the author of this post for this … Read more

Hold the salt: Study reveals how reducing sodium intake can help patients with heart failure

Journal Reference: Justin A Ezekowitz, Eloisa Colin-Ramirez, Heather Ross, Jorge Escobedo, Peter Macdonald, Richard Troughton, Clara Saldarriaga, Wendimagegn Alemayehu, Finlay A McAlister, JoAnne Arcand, John Atherton, Robert Doughty, Milan Gupta, Jonathan Howlett, Shahin Jaffer, Andrea Lavoie, Mayanna Lund, Thomas Marwick, Robert McKelvie, Gordon Moe, A Shekhar Pandey, Liane Porepa, Miroslaw Rajda, Haunnah Rheault, Jitendra Singh, … Read more

Loss of neurons, not lack of sleep, makes Alzheimer’s patients drowsy

Journal Reference: Jun Y. Oh, Christine M. Walsh, Kamalini Ranasinghe, Mihovil Mladinov, Felipe L. Pereira, Cathrine Petersen, Neus Falgàs, Leslie Yack, Tia Lamore, Rakin Nasar, Caroline Lew, Song Li, Thomas Metzler, Quentin Coppola, Natalie Pandher, Michael Le, Hilary W. Heuer, Helmut Heinsen, Salvatore Spina, William W. Seeley, Joel Kramer, Gil D. Rabinovici, Adam L. Boxer, … Read more

Opioid prescriptions for pediatric patients following surgical procedures have dropped significantly

Journal Reference: Tori N. Sutherland, Hannah Wunsch, Craig Newcomb, Scott Hadland, Lakisha Gaskins, Mark D. Neuman. Trends in Routine Opioid Dispensing After Common Pediatric Surgeries in the United States: 2014–2019. Pediatrics, 2022; DOI: 10.1542/peds.2021-054729 Opioids are routinely prescribed after a surgery to help pediatric patients manage mild or moderate pain. However, recent studies have suggested … Read more

Global trial demonstrates some benefits of flu shots for heart failure patients

The study is the first randomized controlled trial to assess the benefits of the flu vaccine specifically in people with heart failure, who face a high risk of cardiovascular events. It was conducted in countries across Asia, Africa and the Middle East where getting a flu shot is not routine for most people. The trial … Read more

Pharmacogenetic testing shows promise improving symptoms in patients with treatment-resistant depression

Journal Reference: Arun K. Tiwari, Clement C. Zai, C. Anthony Altar, Julie-Anne Tanner, Paige E. Davies, Paul Traxler, James Li, Elizabeth S. Cogan, Matthew T. Kucera, Ana Gugila, Nicole Braganza, Heather Emmerson, Gwyneth Zai, Daniel J. Müller, Robert Levitan, Stefan Kloiber, Zafiris J. Daskalakis, Benicio N. Frey, James M. Bowen, Jean-Eric Tarride, Richard Tytus, Ranjith … Read more

Innovative AI technology aids personalized care for diabetes patients needing complex drug treatment

Journal Reference: Shinji Tarumi, Wataru Takeuchi, Rong Qi, Xia Ning, Laura Ruppert, Hideyuki Ban, Daniel H. Robertson, Titus K. Schleyer, Kensaku Kawamoto. Predicting pharmacotherapeutic outcomes for type 2 diabetes: An evaluation of three approaches to leveraging electronic health record data from multiple sources. Journal of Biomedical Informatics, 2022; 104001 DOI: 10.1016/j.jbi.2022.104001 For this smaller group … Read more

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