Landmark study implicates specific genes in schizophrenia

Journal Reference: Vassily Trubetskoy et al. Mapping genomic loci implicates genes and synaptic biology in schizophrenia. Nature, 2022; DOI: 10.1038/s41586-022-04434-5 A group of hundreds of researchers across 45 countries analysed DNA from 76,755 people with schizophrenia and 243,649 without it to better understand the genes and biological processes underpinning the condition. The Psychiatric Genomics Consortium … Read more

‘Switching off’ specific brain cells protects against stress

Journal Reference: Misaki Niu et al. Claustrum mediates bidirectional and reversible control of stress-induced anxiety responses. Science Advances, 2022 DOI: 10.1126/sciadv.abi6375 In a study published this month in Science Advances, researchers from Osaka University discovered a small group of brain cells in the claustrum of mice that controls stress-induced anxiety behaviors. When these cells were … Read more

Study identifies mutations specific to Omicron variant

Journal Reference: Saathvik R. Kannan, Austin N. Spratt, Kalicharan Sharma, Hitendra S. Chand, Siddappa N. Byrareddy, Kamal Singh. Omicron SARS-CoV-2 variant: Unique features and their impact on pre-existing antibodies. Journal of Autoimmunity, 2022; 126: 102779 DOI: 10.1016/j.jaut.2021.102779 The findings help explain how the new variant can escape pre-existing antibodies present in the human body, either … Read more

For IBS, specific diets are less important than expected

Journal Reference: Elise Nordin, Carl Brunius, Rikard Landberg, Per M Hellström. Fermentable oligo-, di-, monosaccharides, and polyols (FODMAPs), but not gluten, elicit modest symptoms of irritable bowel syndrome: a double-blind, placebo-controlled, randomized three-way crossover trial. The American Journal of Clinical Nutrition, 2021; DOI: 10.1093/ajcn/nqab337 “IBS is a very complex disease involving many factors, but our … Read more

Specific components of air pollution identified as more harmful than others

Journal Reference: Pierre Masselot, Francesco Sera, Rochelle Schneider, Haidong Kan, Éric Lavigne, Massimo Stafoggia, Aurelio Tobias, Hong Chen, Richard T. Burnett, Joel Schwartz, Antonella Zanobetti, Michelle L. Bell, Bing-Yu Chen, Yue-Liang Leon Guo, Martina S. Ragettli, Ana Maria Vicedo-Cabrera, Christofer Åström, Bertil Forsberg, Carmen Íñiguez, Rebecca M. Garland, Noah Scovronick, Joana Madureira, Baltazar Nunes, César … Read more